| Grand challenge commentary: Accessing new chemical space for 'undruggable' targets. | |
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MedLine Citation:
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PMID: 21079589 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The synthesis and biological annotation of small molecules from underexplored chemical space will play a central role in the development of drugs for challenging targets currently being identified in frontier areas of biological research such as human genetics. |
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Authors:
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Sivaraman Dandapani; Lisa A Marcaurelle |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nature chemical biology Volume: 6 ISSN: 1552-4469 ISO Abbreviation: Nat. Chem. Biol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-16 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231976 Medline TA: Nat Chem Biol Country: United States |
Other Details:
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Languages: eng Pagination: 861-3 Citation Subset: IM |
Affiliation:
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Chemical Biology Platform, Broad Institute, Cambridge, Massachusetts, USA. sivaram@broadinstitute.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chemistry
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trends Drug Design Drug Discovery / trends* Drug Evaluation, Preclinical Small Molecule Libraries* Synthetic Biology / trends* |
| Chemical | |
Reg. No./Substance:
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0/Small Molecule Libraries |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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