Document Detail


Granatumins A-G, limonoids from the seeds of a Krishna mangrove, Xylocarpus granatum.
MedLine Citation:
PMID:  19888743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Seven new limonoids (1-7), named granatumins A-G, were isolated from seeds of an Indian mangrove (Xylocarpus granatum) collected from the wetlands of Krishna estuary, Andhra Pradesh. The known compounds khayasin T, tigloylseneganolide A, 6-deoxyswietenine, swietemahonolide, febrifugin A, gedunin, xylogranatinin, phaseic acid, (2R,3R)-3,4',5,7-tetrahydroxyflavanone, and (E)-4-hydroxycinnamic acid were also isolated. The structures were established on the basis of spectroscopic data. Granatumins A and B are mexicanolides with endo-conjugated Delta(8,30) and Delta(14,15) double bonds, and granatumins F and G are polyhydroxylated phragmalins found previously in plants of the Meliaceae. Khayasin T exhibited moderate insecticidal activity against fifth instar larvae of Brontispa longissima (Gestro) at a concentration of 20 mg/L.
Authors:
Min-Yi Li; Xiao-Bo Yang; Jian-Yu Pan; Gang Feng; Qiang Xiao; Jari Sinkkonen; Tirumani Satyanandamurty; Jun Wu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of natural products     Volume:  72     ISSN:  1520-6025     ISO Abbreviation:  J. Nat. Prod.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-28     Completed Date:  2010-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906882     Medline TA:  J Nat Prod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2110-4     Citation Subset:  IM    
Affiliation:
Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Beetles / drug effects
Cocos / parasitology
Humans
India
Larva / drug effects
Limonins / chemistry,  isolation & purification*,  pharmacology
Meliaceae / chemistry*
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Diseases / parasitology
Seeds / chemistry
Stereoisomerism
Chemical
Reg. No./Substance:
0/Limonins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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