| Grammar disruption in a patient with Neuro-Sweet syndrome. | |
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MedLine Citation:
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PMID: 21879995 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This paper for the first time reports detailed neurolinguistic findings in a patient with Neuro-Sweet syndrome. In this patient the presenting symptoms of central nervous system (CNS) involvement primarily consisted of a selective grammar deficit restricted to spontaneous speech. On MRI a left prefrontal ischemic stroke (superior part BA 6) and two small subcortical left parietal infarctions were found. Neurolinguistic analyses, however, did not reveal a profile consistent with any observations of agrammatism caused by structural damage to the language areas critically involved in grammatical processing. It is hypothesized that selectively distorted grammar might reflect disruption of the frontosubcortical network involved in language processing. Prefrontal neurobehavioral abnormalities associated with functional disruption of the inferior medial frontal regions as demonstrated by SPECT, additionally suggest that agrammatic symptoms may be linked to a higher-level cognitive disorder following encephalopathic CNS involvement. |
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Authors:
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Peter Mariën; Wim Tops; Roel Crols; Roel Jonkers; Peter P De Deyn; Jo Verhoeven |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-1 |
Journal Detail:
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Title: Neurocase Volume: - ISSN: 1465-3656 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9511374 Medline TA: Neurocase Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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a Department of Neurology and Memory Clinic , ZNA-Middelheim , Antwerp , Belgium. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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