Document Detail


Gradients of CSF monoamine metabolites: a comparison between male and female volunteers.
MedLine Citation:
PMID:  7545235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lumbar puncture at the L4-5 level was performed on 12 healthy male and 12 healthy female volunteers. Confirming previous results, we found pronounced gradients in cerebrospinal fluid (CSF) 5-HIAA and HVA (5-hydroxyindoleacetic acid and homovanillic acid). We also found a gradient in 4-hydroxy-3-methoxyphenylglycol (HMPG), but only in the male volunteers. We also found that tapping-time was significantly longer in females than in males. One reason for this discrepancy may be that an estimate of the spinal distance was greater in males, which might indicate that a hydrodynamic factor plays a role. On taking tapping-time into consideration, the 5-HIAA and HMPG concentrations were significantly higher in males than in females.
Authors:
C Nordin; T Eklundh; V Fernström; A Swedin; A C Zachau
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of psychiatric research     Volume:  29     ISSN:  0022-3956     ISO Abbreviation:  J Psychiatr Res     Publication Date:    1995 Mar-Apr
Date Detail:
Created Date:  1995-10-10     Completed Date:  1995-10-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376331     Medline TA:  J Psychiatr Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  133-40     Citation Subset:  IM    
Affiliation:
Department of Clinical Neuroscience and Family Medicine, Karolinska Institute, Huddinge Hospital, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adult
Arousal / physiology
Body Height / physiology
Body Weight / physiology
Female
Homovanillic Acid / cerebrospinal fluid*
Humans
Hydroxyindoleacetic Acid / cerebrospinal fluid*
Male
Methoxyhydroxyphenylglycol / cerebrospinal fluid*
Middle Aged
Reaction Time / physiology
Reference Values
Sex Characteristics*
Chemical
Reg. No./Substance:
306-08-1/Homovanillic Acid; 534-82-7/Methoxyhydroxyphenylglycol; 54-16-0/Hydroxyindoleacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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