| Gradient-echo imaging of hemorrhage at 1.5 Tesla. | |
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MedLine Citation:
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PMID: 2716484 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report in vitro and in vivo MR studies of hemorrhage using the gradient-echo pulse sequence, FISP (steady state free precession) and FLASH (spoiling of transverse magnetization) at 1.5 Tesla. Phantoms containing methemoglobin, ferromagnetic particles, human serum and blood clot were scanned using both spin-echo and gradient-echo techniques. FLASH signal intensities were more sensitive to methemoglobin concentration than high T1-weighted spin-echo images. FISP showed little change in signal intensity with varying concentrations of methemoglobin and a contrast relationship similar to T2-weighted spin-echo techniques. FISP and FLASH showed intensity changes at lower concentrations of ferromagnetic material than T2-weighted spin-echo sequences. In vitro blood clot was less intense when observed by FISP and FLASH sequences than on the T2-weighted spin-echo sequences. Maximum contrast between clot and other blood components occurred at a flip angle of 45 degrees for FLASH and 60 degrees for FISP. FISP and FLASH scans of patients with hemorrhage demonstrated a marked decrease in signal intensity in the region of blood clot. This decrease was more pronounced with the gradient-echo sequences than with T2-weighted spin-echo images. We conclude that FLASH is useful for detecting methemoglobin and that both FISP and FLASH are useful for evaluating hemorrhage because of their sensitivity to methemoglobin. |
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Authors:
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E C Unger; M S Cohen; T R Brown |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Magnetic resonance imaging Volume: 7 ISSN: 0730-725X ISO Abbreviation: Magn Reson Imaging Publication Date: 1989 Mar-Apr |
Date Detail:
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Created Date: 1989-06-19 Completed Date: 1989-06-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8214883 Medline TA: Magn Reson Imaging Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 163-72 Citation Subset: IM |
Affiliation:
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Department of Radiology, Fox Chase Cancer Center, Philadelphia, PA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cerebral Hemorrhage / diagnosis* Female Humans Magnetic Resonance Imaging / methods* Male Middle Aged Models, Structural |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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