| Gradient compression garments as a countermeasure to post-spaceflight orthostatic intolerance. | |
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MedLine Citation:
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PMID: 20824997 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Post-spaceflight orthostatic intolerance affects approximately 30% of short-duration and 80% of long-duration crewmembers. While the current NASA antigravity suit is effective during Space Shuttle re-entry, it is not designed to be worn postflight and has several drawbacks. The purpose of this study was to evaluate the use of commercially available, thigh-high, gradient compression garments to prevent post-spaceflight orthostatic intolerance. METHODS: Before spaceflight, five male Shuttle astronauts were fitted for compression garments. Postflight stand time, blood pressure, heart rate, stroke volume, cardiac output, and peripheral resistance during 10-min, 80 degrees head-up tilt test within 4 h of landing in these astronauts were retrospectively compared to a group of nine male astronauts not wearing the compression garments. RESULTS: On landing day, three of nine non-countermeasure astronauts developed presyncopal symptoms and could not complete the test, while no countermeasure subjects became presyncopal. Compared to the non-countermeasure subjects, the countermeasure subjects had higher systolic blood pressure (116 +/- 3 vs. 134 +/- 2 mmHg), stroke volume (42 +/- 5 vs. 57 +/- 6 ml), and cardiac output (3.1 +/- 0.3 vs. 4.6 +/- 0.4 L). Heart rate was not different between groups. CONCLUSIONS: In this small pilot study, the rate of presyncope in the non-countermeasure group was similar to that reported previously in subjects without a compression garment. In contrast, thigh-high graded compression garments mitigated the symptoms of orthostatic intolerance by improving stroke volume, cardiac output, and systolic blood pressure responses to standing. |
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Authors:
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Michael B Stenger; Angela K Brown; Stuart M C Lee; James P Locke; Steven H Platts |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Aviation, space, and environmental medicine Volume: 81 ISSN: 0095-6562 ISO Abbreviation: Aviat Space Environ Med Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-09 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501714 Medline TA: Aviat Space Environ Med Country: United States |
Other Details:
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Languages: eng Pagination: 883-7 Citation Subset: IM; S |
Affiliation:
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Integrated Science and Engineering Group, NASA/Johnson Space Center, 1290 Hercules Drive, Houston, TX 77058, USA. michael.b.stenger@nasa.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Humans Intermittent Pneumatic Compression Devices* Male Middle Aged Orthostatic Intolerance / prevention & control* Pilot Projects Space Flight* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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