| Gout and coronary artery disease: epidemiologic clues. | |
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MedLine Citation:
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PMID: 18638434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gout is the leading cause of inflammatory arthritis, typically affecting men and characterized by intermittent, abrupt onset of intense inflammation. The association between gout, atherosclerosis, and vascular disease has been noted in medical literature since the end of the 19th century, yet it has not been well studied. This review critically appraises the few epidemiologic studies that ask if gout is a risk factor for coronary artery disease. An exhaustive literature search using search engines and cross-referencing found four major studies and several smaller studies that have evaluated gout as a risk factor for coronary artery disease. The available studies were too heterogeneous to permit formal meta-analysis. Although there are gaps in evidence pointing to a causative pathway, overall, evidence exists for a relationship between gouty arthritis and coronary artery disease independent of traditional risk factors. |
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Authors:
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Eswar Krishnan |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current rheumatology reports Volume: 10 ISSN: 1534-6307 ISO Abbreviation: Curr Rheumatol Rep Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-07-21 Completed Date: 2008-09-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888970 Medline TA: Curr Rheumatol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 249-55 Citation Subset: IM |
Affiliation:
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S709 BST South, 3500 Terrace Street, Pittsburgh, PA 15215, USA. arthritis.md@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Comorbidity Coronary Artery Disease / epidemiology*, metabolism, physiopathology Gout / epidemiology*, metabolism, physiopathology Humans Male Oxidative Stress Prospective Studies Risk Factors |
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