Document Detail

Gorham disease of the spine: a case report and treatment strategies for this enigmatic bone disease.
MedLine Citation:
PMID:  15673977     Owner:  NLM     Status:  MEDLINE    
Gorham disease is an extremely rare condition of unknown etiology characterized by progressive osteolysis. Only 28 cases of its spinal involvement have been reported, and some of those cases showed kyphosis, kyphoscoliosis, subluxation or dislocation. No definite regimen of treatment has been established yet. A 10-year-old boy presented with a severe and progressive kyphosis over 90 degrees caused by Gorham disease from T3 to T12. In situ posterior fusion with a hook and rod system and iliac bone grafts were performed, but after surgery, he had complete paraplegia and its cause was uncertain. Based on the unfortunate consequence of the present case and the review of the literature, we propose the treatment strategies for spinal Gorham disease.
Toshimi Aizawa; Tetsuro Sato; Shoichi Kokubun
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  205     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-01-27     Completed Date:  2005-05-20     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  187-96     Citation Subset:  IM    
Department of Orthopedic Surgery, Tohoku University School of Medicine, Aoba-ku, Sendai, Japan.
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MeSH Terms
Follow-Up Studies
Magnetic Resonance Imaging
Osteolysis, Essential / pathology*,  surgery,  therapy*
Spine / pathology*,  radiography,  surgery

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