| Gordonan, an acidic polysaccharide with cell aggregation-inducing activity in insect BM-N4 cells, produced by Gordonia sp. | |
| | |
MedLine Citation:
|
PMID: 11193406 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
An acidic polysaccharide, termed gordonan, was isolated from the culture medium of Gordonia sp. as an inducer of cell aggregation in an insect cell line, BM-N4. Gordonan had an average molecular weight of 5 x 10(6) and its structure was identified as -->3)-4-O-(1-carboxyethyl)-beta-D-Manp-(1-->4)-beta-D-GlcAp-(1-->4)-beta-D-Glcp-(1--> mainly by acid hydrolysis experiments and NMR analysis. It induces cell aggregation at the concentration of 4 microg/ml. A partially hydrolyzed polysaccharide derived from gordonan with a molecular weight of 5 x 10(5) showed weak activity, while any fragment molecules with lower molecular weights prepared from gordonan showed no activity. |
| | |
Authors:
|
T Kondo; D Yamamoto; A Yokota; A Suzuki; H Nagasawa; S Sakuda |
Related Documents
:
|
10549806 - Primary cultures of neuronal and non-neuronal rat brain cells secrete similar proportio... 15770146 - Nuclear translocation of beta-catenin in developing auditory epithelia of mice. 7767866 - Lipid esterification and synthesis by the iec-6 intestinal epithelial crypt cell line: ... 12874456 - Bioengineered implantation of megalin-expressing cells: a potential intracorporeal ther... 17954316 - Clinicopathological and immunocytochemical study of multifocal epithelial hyperplasia. 21637416 - Co-localization of gstp1 and jnk in transitional cell carcinoma of urinary bladder. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Bioscience, biotechnology, and biochemistry Volume: 64 ISSN: 0916-8451 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2000 Nov |
Date Detail:
|
Created Date: 2001-01-19 Completed Date: 2001-03-08 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
|
Languages: eng Pagination: 2388-94 Citation Subset: IM |
Affiliation:
|
Department of Applied Biological Chemistry, The University of Tokyo, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Actinomycetales
/
chemistry* Animals Cell Aggregation / drug effects Cells, Cultured Fermentation Insects Magnetic Resonance Spectroscopy Polysaccharides / chemistry, isolation & purification*, pharmacology Polysaccharides, Bacterial / chemistry, isolation & purification*, pharmacology |
| Chemical | |
Reg. No./Substance:
|
0/Polysaccharides; 0/Polysaccharides, Bacterial; 0/gordonan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Qualitative and quantitative analysis of endogenous jasmonoids in potato plant (Solanum tuberosum L....
Next Document: Dietary antioxidants fail in protection against oxidative genetic damage in in vitro evaluation.