Document Detail

Goodpasture syndrome in a pregnant woman.
MedLine Citation:
PMID:  16260570     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Goodpasture syndrome, an immunologic disorder characterized by glomerulonephritis and pulmonary hemorrhage, rarely presents in pregnancy. CASE: We describe a patient who was diagnosed with Goodpasture syndrome in her second trimester. She required daily hemodialysis, intermittent plasmapheresis, and immunosuppressive therapy. Her pregnancy was complicated by hypertension, and she delivered a low birth weight neonate prematurely at 26 4/7 weeks of gestation by cesarean due to nonreassuring fetal status. Deterioration in the fetal status may have been secondary to complications of hypertension, in addition to prematurity. CONCLUSION: Goodpasture syndrome in pregnancy may be associated with significant maternal and fetal morbidity.
D Marie Vasiliou; Cynthia Maxwell; Prakeshkumar Shah; Mathew Sermer
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  106     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-01     Completed Date:  2006-02-03     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1196-9     Citation Subset:  AIM; IM    
Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
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MeSH Terms
Anti-Glomerular Basement Membrane Disease / diagnosis*,  therapy
Cesarean Section*
Glomerulonephritis / etiology,  therapy
Hemorrhage / etiology
Hypertension / etiology
Infant, Newborn
Infant, Premature
Pregnancy Complications / diagnosis*,  therapy
Pregnancy Outcome
Pregnancy Trimester, Second
Renal Dialysis

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