Document Detail

Good prognosis for dilated cardiomyopathy without severe heart failure or arrhythmia.
MedLine Citation:
PMID:  2385738     Owner:  NLM     Status:  MEDLINE    
In 124 patients with dilated cardiomyopathy, symptoms of heart failure and ventricular arrhythmia at initial assessment were related to outcome a mean of 43 months later. Using life table analysis, the two-year mortality from progressive heart failure was 59 per cent (90 per cent symptoms, six per cent (1-11 per cent) for patients with class 2 symptoms and zero for patients with class 1 symptoms. The two-year mortality from sudden death was 18 per cent (5-32 per cent) for patients with class 3 symptoms, eight per cent (3-14 per cent) for patients with class 2 symptoms and seven per cent (0-17 per cent) for patients with class 1 symptoms. Sudden death was more frequent in patients with ventricular tachycardia or frequent ventricular ectopics, irrespective of the severity of heart failure (15 per cent (7-23 per cent) vs. three per cent (0-8 per cent) at two years). These findings suggest that patients with dilated cardiomyopathy and mild symptoms often have a benign clinical course. However, occult ventricular arrhythmia is associated with an increased risk of sudden death.
R A Stewart; W J McKenna; C M Oakley
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Quarterly journal of medicine     Volume:  74     ISSN:  0033-5622     ISO Abbreviation:  Q. J. Med.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-09-20     Completed Date:  1990-09-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401027     Medline TA:  Q J Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  309-18     Citation Subset:  IM    
Department of Medicine, Hammersmith Hospital, Royal Postgraduate Medical School, London.
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MeSH Terms
Arrhythmias, Cardiac / mortality
Cardiomyopathy, Dilated / mortality*
Cause of Death
Heart Failure / mortality
Life Tables
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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