| Good pregnancy outcome despite intrahepatic cholestasis. | |
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MedLine Citation:
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PMID: 20429741 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Pregnant women complaining of itching are screened for intrahepatic cholestasis (ICP) by laboratory tests in primary healthcare. Cases of ICP are referred to specialist care. In Finland, ICP occurs in 1% of pregnancies. The aim was to study the outcome of deliveries. Design. Retrospective study of ICP pregnancies. Data were collected from the hospital discharge register, patient records, and the labour register. SETTING: The region of Tampere University Hospital in Finland. SUBJECTS: Altogether 687 ICP cases from 1969 to 1988 and two controls for each. Main outcome measures. ICP patients were compared with controls in terms of mother's age, pregnancy multiplicity, weeks of gestation at delivery, frequency of induction and Caesarean section, length of ward period, child's weight, Apgar scores, and stillbirth. RESULTS: For ICP patients, the risk for hospital stay of 10 days or more was eightfold (OR 8.41), for gestational weeks less than 37 at delivery sevenfold (OR 7.02), for induction threefold (OR 3.26), for baby's low weight at birth almost twofold (OR 1.86), and for Caesarean section one and a half fold (OR 1.47). The possibility of the incidence of multiple pregnancy was two and a half fold (OR 2.49, 95%). ICP was not associated with mother's age, the baby's risk of stillbirth, or low Apgar scores. CONCLUSION: ICP mothers are found and taken care of appropriately, and thus ICP is only a minor risk for mothers and their children. |
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Authors:
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Kaisa Turunen; Markku Sumanen; Riitta-Liisa Haukilahti; Pertti Kirkinen; Kari Mattila |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Scandinavian journal of primary health care Volume: 28 ISSN: 1502-7724 ISO Abbreviation: Scand J Prim Health Care Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2010-05-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8510679 Medline TA: Scand J Prim Health Care Country: England |
Other Details:
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Languages: eng Pagination: 102-7 Citation Subset: IM |
Affiliation:
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Medical School, Department of General Practice, University of Tampere, Finland. kaisa.turunen@uta.fi |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cesarean Section Cholestasis, Intrahepatic / complications*, diagnosis, therapy Delivery, Obstetric Family Practice Female Humans Infant, Newborn Length of Stay Maternal Age Maternal Health Services Pregnancy Pregnancy Complications* / diagnosis, therapy Pregnancy Outcome* Retrospective Studies Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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