| Good intentions: risk factors for unintended pregnancies in the US cohort of a microbicide trial. | |
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MedLine Citation:
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PMID: 21134507 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: The study was conducted to assess socio-behavioral and biological factors associated with unplanned pregnancy in the US cohort of a microbicide trial. STUDY DESIGN: We conducted a mixed-method, nested case-control study of risk factors for pregnancy within the US cohort of the microbicide trial HPTN 035. We developed an instrument to assess attitudes and beliefs about fertility control/contraceptive utilization among 122 women. Cases were HPTN 035 participants who became pregnant while enrolled, matched by time on study 1:4 with controls. Univariable and multivariable analysis were performed with pregnancy as the outcome of interest. RESULTS: Contraceptive method change during the trial was associated with unplanned pregnancy (OR=1.76). Participant desire/partners' desire for future children (OR=4.95) and young age (OR=0.88 annually above age 19 years) were independently associated with unintended pregnancy. CONCLUSION: Within a trial that enroll heterosexually active women, there may be ways to identify those at highest risk of becoming pregnant a priori. |
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Authors:
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Courtney A Schreiber; Sara Whittington; Liyi Cen; Lisa Maslankowski |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-08-05 |
Journal Detail:
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Title: Contraception Volume: 83 ISSN: 1879-0518 ISO Abbreviation: Contraception Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0234361 Medline TA: Contraception Country: United States |
Other Details:
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Languages: eng Pagination: 74-81 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. cschreiber@obgyn.upenn.edu |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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U01AI068633/AI/NIAID NIH HHS; U01AI46749/AI/NIAID NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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