Document Detail


Good intentions: risk factors for unintended pregnancies in the US cohort of a microbicide trial.
MedLine Citation:
PMID:  21134507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The study was conducted to assess socio-behavioral and biological factors associated with unplanned pregnancy in the US cohort of a microbicide trial.
STUDY DESIGN: We conducted a mixed-method, nested case-control study of risk factors for pregnancy within the US cohort of the microbicide trial HPTN 035. We developed an instrument to assess attitudes and beliefs about fertility control/contraceptive utilization among 122 women. Cases were HPTN 035 participants who became pregnant while enrolled, matched by time on study 1:4 with controls. Univariable and multivariable analysis were performed with pregnancy as the outcome of interest.
RESULTS: Contraceptive method change during the trial was associated with unplanned pregnancy (OR=1.76). Participant desire/partners' desire for future children (OR=4.95) and young age (OR=0.88 annually above age 19 years) were independently associated with unintended pregnancy.
CONCLUSION: Within a trial that enroll heterosexually active women, there may be ways to identify those at highest risk of becoming pregnant a priori.
Authors:
Courtney A Schreiber; Sara Whittington; Liyi Cen; Lisa Maslankowski
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-08-05
Journal Detail:
Title:  Contraception     Volume:  83     ISSN:  1879-0518     ISO Abbreviation:  Contraception     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-07     Completed Date:  2011-04-18     Revised Date:  2014-10-26    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  74-81     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Anti-Infective Agents / administration & dosage*
Case-Control Studies
Cohort Studies
Female
HIV Infections / prevention & control*
Humans
Incidence
Logistic Models
Philadelphia
Pregnancy
Pregnancy, Unplanned / psychology*
Questionnaires
Risk Factors
Grant Support
ID/Acronym/Agency:
P30 AI045008/AI/NIAID NIH HHS; U01AI068633/AI/NIAID NIH HHS; U01AI46749/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Infective Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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