Document Detail

Gonadal steroids and attentional mechanisms in young domestic chicks.
MedLine Citation:
PMID:  3194463     Owner:  NLM     Status:  MEDLINE    
Chicks trained to take a food reward at the end of a runway can be distracted by changes in the appearance of either the food dish towards which they are running or of the walls of the runway remote from the food dish. Testosterone (administered as a long lasting ester 48 hours before testing) increases distraction produced by the former and decreases distraction produced by the latter manipulation. Here it is shown that these effects can be mimicked by an appropriate dose of estradiol given 30 minutes before testing. Higher doses of estradiol increase distraction (relative to controls) in both tests. The central mechanism underlying these effects may be closely linked to or identical with that responsible for the effects of testosterone on a passive avoidance task described elsewhere; these effects are also estrogenic and occur at short latency. The mechanism itself is likely to influence aspects of attention and memory processing.
P G Clifton; R J Andrew; L Brighton
Related Documents :
20836593 - The phylogenetic roots of cognitive dissonance.
11165213 - Can rhesus monkeys spontaneously subtract?
23638313 - Evaluation of banana hypersensitivity among a group of atopic egyptian children: relati...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physiology & behavior     Volume:  43     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1988  
Date Detail:
Created Date:  1989-01-11     Completed Date:  1989-01-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  441-6     Citation Subset:  IM    
School of Biological Sciences, University of Sussex, Brighton.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Attention / drug effects*
Conditioning, Operant / drug effects*
Dose-Response Relationship, Drug
Estradiol / analogs & derivatives*,  pharmacology
Motor Activity / drug effects
Testosterone / pharmacology*
Reg. No./Substance:
113-38-2/estradiol dipropionate; 50-28-2/Estradiol; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Response of circadian locomotor activity and the proestrous luteinizing hormone surge to phase shift...
Next Document:  Biochemical energetics of hierarchy formation in Betta splendens.