Document Detail


A Gompertz age-specific mortality rate model of aging: modification by dietary restriction in rats.
MedLine Citation:
PMID:  2636134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A Gompertz age-specific mortality rate model characterizing actuarial effects of food restriction in rats was developed based on mortality data from the study of Yu et al. (J. Gerontol. 40: 657-670, 1985). Results indicated that in the presence of adequate nutrition, food restriction reduces the aging rate parameter in a consistent manner, regardless of the age at which food restriction is initiated.
Authors:
P J Neafsey; H Boxenbaum; D A Ciraulo; D J Fournier
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Drug metabolism reviews     Volume:  21     ISSN:  0360-2532     ISO Abbreviation:  Drug Metab. Rev.     Publication Date:  1989  
Date Detail:
Created Date:  1990-06-25     Completed Date:  1990-06-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0322067     Medline TA:  Drug Metab Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  351-65     Citation Subset:  IM    
Affiliation:
Tufts University School of Medicine, Boston, Massachusetts.
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MeSH Terms
Descriptor/Qualifier:
Aging / physiology*
Animals
Diet*
Male
Models, Biological*
Mortality*
Proportional Hazards Models
Rats
Rats, Inbred F344

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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