| Goldmann Applanation Tonometry and Dynamic Contour Tonometry are not Correlated With Central Corneal Thickness in Primary Open Angle Glaucoma. | |
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MedLine Citation:
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PMID: 20577097 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To compare intraocular pressure (IOP) measured by Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) and assess their relationship to central corneal thickness (CCT) in patients with primary open angle glaucoma (OAG). PATIENTS AND METHODS: GAT, DCT, and CCT were assessed in 116 patients with OAG [mean age 65.9 (10.5); 59% female] participating in the Indianapolis Glaucoma Progression Study. GAT and DCT were measured in a randomized order followed by CCT (ultrasonic corneal pachymetry) during a single study visit. Bland-Altman plots were used to evaluate the limits of agreement between tonometery methodologies whereas multivariate regression analysis was used to evaluate the influence of CCT on GAT and DCT IOP measurements. RESULTS: IOP values obtained by DCT and GAT showed a strong positive correlation in patients with OAG (r=0.93; P<0.001). Mean IOP measured with DCT [18.4 (5.1) mm Hg] was significantly higher (P<0.001) than GAT IOP measurements [16.5 (4.5) mmHg]. CCT did not seem to influence either GAT or DCT measurements (r=0.1025, P=0.16; r=0.05, P=0.46), respectively. The Bland-Altman data showed that the amount of disagreement between IOP assessment techniques varied, suggesting a proportional bias. CONCLUSIONS: In this group of patients with OAG, there was a strong correlation between GAT and DCT measurements of IOP. IOP measured with DCT was consistently higher than IOP measured with GAT. Neither GAT nor DCT measurements were correlated with CCT. This data suggests that factors other than CCT may be involved in the tendency of DCT to produce higher measures of IOP than GAT. |
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Authors:
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Guy Regev; Alon Harris; Brent Siesky; Yochai Shoshani; Patrick Egan; Adam Moss; Miriam Zalish; Darrell Wudunn; Rita Ehrlich |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of glaucoma Volume: 20 ISSN: 1536-481X ISO Abbreviation: J. Glaucoma Publication Date: 2011 Jun-Jul |
Date Detail:
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Created Date: 2011-06-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9300903 Medline TA: J Glaucoma Country: United States |
Other Details:
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Languages: eng Pagination: 282-6 Citation Subset: IM |
Affiliation:
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*Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN †Kaplan MC Department of Ophthalmology, Rehovot, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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