Document Detail

Gold nanoparticles and oxidative stress in Mytilus edulis.
MedLine Citation:
PMID:  18378295     Owner:  NLM     Status:  MEDLINE    
Little is known about potential environmental impact of nanoparticles. Gold nanoparticles can cause unexpected biological responses. Here, Mytilus edulis were exposed (24h) to gold-citrate nanoparticles (GNP), menadione and both compounds simultaneously (GNP/menadione). Protein ubiquitination and carbonylation were determined in gill, mantle and digestive gland, along with traditional oxidative stress biomarkers; catalase activity and neutral red retention time assay (haemolymph). 2DE gels were performed on gill proteins (menadione; GNP/menadione). Our results reveal that GNP may induce oxidative stress.
S Tedesco; H Doyle; G Redmond; D Sheehan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-02-26
Journal Detail:
Title:  Marine environmental research     Volume:  66     ISSN:  0141-1136     ISO Abbreviation:  Mar. Environ. Res.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-16     Completed Date:  2008-09-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9882895     Medline TA:  Mar Environ Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  131-3     Citation Subset:  IM    
Proteomics Research Group, Department of Biochemistry, Environmental Research Institute, University College Cork, Cork, Ireland.
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MeSH Terms
Gills / drug effects
Gold / toxicity*
Metal Nanoparticles / toxicity*
Mytilus edulis / drug effects*,  metabolism*
Oxidative Stress / drug effects*
Vitamin K 3 / toxicity
Reg. No./Substance:
58-27-5/Vitamin K 3; 7440-57-5/Gold

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