Document Detail


Gold nanoparticles: an era in bionanotechnology.
MedLine Citation:
PMID:  23289421     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Gold nanoparticles have been efficiently and effectively used for the delivery of biomolecules and genes along with the potential to offer extremely sensitive diagnostics and imaging methods.
AREAS COVERED: This review discusses the historical aspects, synthesis of gold nanoparticles, gold nanoparticles as drug delivery vehicles, photothermal effect of gold nanoparticles and the applications of gold nanoparticles. Gold nanoparticles with their unique optical properties may be useful as biosensors in living cells and has application in the field of drug delivery and photothermal therapy. Depending on the size, shape and degree of aggregation and nature of the protecting organic shells on their surface, gold nanoparticles can appear red, blue and other colors and emit bright resonance light of various wavelengths, which falls under visible region. Because of this property, gold nanoparticles have been extensively used as probes for sensing/imaging a wide range of analysts/targets such as proteins, cells and nucleic acids.
EXPERT OPINION: Gold nanoparticles provide an admirable platform for the delivery of biomolecules and genes.
Authors:
Deepak Kumar; Nisha Saini; Nitin Jain; Rashmi Sareen; Vinay Pandit
Publication Detail:
Type:  Journal Article; Review     Date:  2013-01-07
Journal Detail:
Title:  Expert opinion on drug delivery     Volume:  10     ISSN:  1744-7593     ISO Abbreviation:  Expert Opin Drug Deliv     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-15     Completed Date:  2013-05-20     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  101228421     Medline TA:  Expert Opin Drug Deliv     Country:  England    
Other Details:
Languages:  eng     Pagination:  397-409     Citation Subset:  IM    
Affiliation:
Shoolini University, School of Pharmaceutical Sciences, Solan H.P, India.
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MeSH Terms
Descriptor/Qualifier:
Diagnostic Imaging / methods
Drug Delivery Systems*
Gold / chemistry*
Humans
Nanoparticles / chemistry*
Nanotechnology
Chemical
Reg. No./Substance:
7440-57-5/Gold

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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