Document Detail


Gold nanoparticle-based assays for the detection of biologically relevant molecules.
MedLine Citation:
PMID:  18694316     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Metallic nanoparticles of different sizes, shapes and compositions are being avidly explored as materials for next-generation biological labels, therapeutic agents, 'artificial viruses' and diagnostic probes. Gold nanoparticles especially, are making a major impact in these areas, owing in large part to their ease of functionality, low toxicity and unique optical properties. In particular, gold nanoparticles are having a major role in the development of highly sensitive and selective assays for biologically relevant molecules. Some of the assays for nucleic acids and proteins developed in the last 10 years outperform established methods and may soon find routine use in hospital settings.
Authors:
Kiley A White; Nathaniel L Rosi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nanomedicine (London, England)     Volume:  3     ISSN:  1748-6963     ISO Abbreviation:  Nanomedicine (Lond)     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-12     Completed Date:  2009-01-06     Revised Date:  2010-01-28    
Medline Journal Info:
Nlm Unique ID:  101278111     Medline TA:  Nanomedicine (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  543-53     Citation Subset:  IM    
Affiliation:
Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenosine / analysis,  chemistry
Biosensing Techniques / instrumentation,  methods*
Gold / chemistry*
Metal Nanoparticles / chemistry*
Nanotechnology / instrumentation,  methods*
Nucleic Acids / analysis,  chemistry
Reproducibility of Results
Chemical
Reg. No./Substance:
0/Nucleic Acids; 58-61-7/Adenosine; 7440-57-5/Gold

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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