Document Detail


Gold nanoparticle as an alternative tool for a urine pregnancy test.
MedLine Citation:
PMID:  18935992     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The urine pregnancy test is an easily available diagnostic test in the present day and is routinely performed. The test is based on an immunochromatography technique. Here, we used an advanced nanomedicine technique for modification of the urine pregnancy test. MATERIALS AND METHODS: The preparation of gold nanoparticle solution in this study followed the standard method. We performed an experiment on both pregnancy-positive and -negative urine samples. First, a mixture with an equal amount (500 microliters) of gold nanoparticle solution and urine sample was prepared. Then, it was further tested for pregnancy by the urine pregnancy test strip. RESULTS: The pregnancy-positive mixture became pink, while the pregnancy-negative mixture became gray. The urine pregnancy test strip for a positive mixture had two lines, while the negative mixture had one line. CONCLUSION: This application can help the diagnosis of pregnancy and can be an alternative method for a urine pregnancy test. To our knowledge, this is the first report on this application.
Authors:
Rojrit Rojanathanes; Amornpun Sereemaspun; Nuttaporn Pimpha; Vanida Buasorn; Prapawadee Ekawong; Viroj Wiwanitkit
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Taiwanese journal of obstetrics & gynecology     Volume:  47     ISSN:  1875-6263     ISO Abbreviation:  -     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-21     Completed Date:  2009-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101213819     Medline TA:  Taiwan J Obstet Gynecol     Country:  China    
Other Details:
Languages:  eng     Pagination:  296-9     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Gold / diagnostic use*
Humans
Metal Nanoparticles / diagnostic use*
Pregnancy
Pregnancy Tests / methods*
Reference Values
Sampling Studies
Sensitivity and Specificity
Thailand
Urinalysis
Urine / chemistry*
Young Adult
Chemical
Reg. No./Substance:
7440-57-5/Gold

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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