| Glyphosate: a once-in-a-century herbicide. | |
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MedLine Citation:
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PMID: 18273882 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Since its commercial introduction in 1974, glyphosate [N-(phosphonomethyl)glycine] has become the dominant herbicide worldwide. There are several reasons for its success. Glyphosate is a highly effective broad-spectrum herbicide, yet it is very toxicologically and environmentally safe. Glyphosate translocates well, and its action is slow enough to take advantage of this. Glyphosate is the only herbicide that targets 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS), so there are no competing herbicide analogs or classes. Since glyphosate became a generic compound, its cost has dropped dramatically. Perhaps the most important aspect of the success of glyphosate has been the introduction of transgenic, glyphosate-resistant crops in 1996. Almost 90% of all transgenic crops grown worldwide are glyphosate resistant, and the adoption of these crops is increasing at a steady pace. Glyphosate/glyphosate-resistant crop weed management offers significant environmental and other benefits over the technologies that it replaces. The use of this virtually ideal herbicide is now being threatened by the evolution of glyphosate-resistant weeds. Adoption of resistance management practices will be required to maintain the benefits of glyphosate technologies for future generations. |
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Authors:
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Stephen O Duke; Stephen B Powles |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Pest management science Volume: 64 ISSN: 1526-498X ISO Abbreviation: Pest Manag. Sci. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-19 Completed Date: 2008-06-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100898744 Medline TA: Pest Manag Sci Country: England |
Other Details:
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Languages: eng Pagination: 319-25 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2008 Society of Chemical Industry. |
Affiliation:
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USDA-ARS, Natural Products Utilization Research Unit, National Center for Natural Products Research, PO Box 8048, University, MS 38677, USA. sduke@ole.miss.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Crops, Agricultural
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genetics* Evolution Glycine / analogs & derivatives* Herbicide Resistance / genetics Herbicides* Plants, Genetically Modified* |
| Chemical | |
Reg. No./Substance:
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0/Herbicides; 1071-83-6/glyphosate; 56-40-6/Glycine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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