Document Detail


Glycosylated nordihydroguaiaretic acids as anti-cancer agents.
MedLine Citation:
PMID:  21123067     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Three perglycosylated nordihydroguaiaretic acids (NDGA) were synthesized through the Huiseng 1,3-dipolar cycloaddition reaction. These sugar-NDGA conjugates containing triazole-linkages possessed good solubility in water. NDGA-(triazol-galactose)(4) (12b) and NDGA-(triazol-glucose)(4) (12c) were found to act as inhibitors against human hepatocellular carcinoma Hep3B cells in culture.
Authors:
Jih Ru Hwu; Chuan-I Hsu; Ming-Hua Hsu; Yu-Chuan Liang; Ru Chih C Huang; Yuan C Lee
Related Documents :
10862147 - Chemiluminescence and reactive oxygen scavenging activities of the hydrogen peroxide/ga...
21535677 - Effect of cassava starch coating on quality and shelf life of fresh-cut pineapple (anan...
21202647 - Cholic acid-quinoxaline (2/1).
16884747 - Lipoxygenases during brassica napus seed germination.
3938407 - Sulphur amino-acid degradation in subjects with hereditary glutathione synthetase defic...
6433987 - Pentane formation during the anaerobic reactions of reticulocyte lipoxygenase. comparis...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-10-31
Journal Detail:
Title:  Bioorganic & medicinal chemistry letters     Volume:  21     ISSN:  1464-3405     ISO Abbreviation:  Bioorg. Med. Chem. Lett.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107377     Medline TA:  Bioorg Med Chem Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  380-2     Citation Subset:  IM    
Copyright Information:
Copyright © 2010. Published by Elsevier Ltd.
Affiliation:
Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan, ROC. jrhwu@mx.nthu.edu.tw
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.
Next Document:  Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata.