Document Detail

Glycosaminoglycans in the bronchial mucus of patients with chronic bronchitis and mucoid impaction of the bronchus.
MedLine Citation:
PMID:  4010457     Owner:  NLM     Status:  MEDLINE    
Glycosaminoglycans were isolated from mucus of patients with chronic bronchitis and mucoid impaction of the bronchus, whose contents were approximately 56 mumoles and 80 mumoles of hexosamine per g of dry weight of mucus respectively. Electrophoretic and chemical characterization and enzymatic susceptibility demonstrated that the glycosaminoglycans in mucus from both groups of the patients contained hyaluronic acid as the main constituent, with undersulphated chondroitin as a minor component. In addition, in mucus from the patient with mucoid impaction of the bronchus chondroitin sulphate and heparan sulphate or heparan sulphate-like substance were identified.
D A Theocharis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences     Volume:  36     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1985 Jun 
Date Detail:
Created Date:  1985-07-30     Completed Date:  1985-07-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2287-93     Citation Subset:  IM    
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MeSH Terms
Bronchial Diseases / metabolism*
Bronchitis / metabolism*
Chemical Fractionation
Chondroitinases and Chondroitin Lyases
Chromatography, Gel
Electrophoresis, Cellulose Acetate
Galactosamine / analysis
Glucosamine / analysis
Glycosaminoglycans / isolation & purification*
Hexosamines / analysis
Hexoses / analysis
Middle Aged
Mucus / analysis*
Sulfates / analysis
Uronic Acids / analysis
Reg. No./Substance:
0/Glycosaminoglycans; 0/Hexosamines; 0/Hexoses; 0/Sulfates; 0/Uronic Acids; 3416-24-8/Glucosamine; 7535-00-4/Galactosamine; EC; EC 4.2.2.-/Chondroitinases and Chondroitin Lyases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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