Document Detail

Glycolic acid peeling in the treatment of acne.
MedLine Citation:
PMID:  10343939     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Glycolic acid chemical peels have been widely accepted as a useful modality in many cutaneous conditions characterized by abnormalities of keratinization. OBJECTIVE: The aim of this study is to evaluate the use of glycolic peels in the main clinical forms of acne. METHODS: Between January 1995 and December 1996, 80 women, aged 13-40 years, were visited for acne and selected for the study at the Cagliari University Dermatology Department (Italy). The type and severity of acne in each patient was assessed following the Leeds technique. The chemical peels were performed with a 70% glycolic acid solution, for times that varied in a range between 2 and 8 minutes. The number and frequency of the applications depended on the intensity of the clinical response. RESULTS: The main clinical forms were comedonic acne in 32 cases, papulo-pustular acne in 40 cases and nodule-cystic acne in the remaining eight cases. The most rapid improvement was observed in comedonic acne. In the papulo-pustular forms an average of six applications was necessary. Although nodular-cystic forms required eight to ten applications, a significant improvement of the coexisting post-acne superficial scarring was noted. The procedure was well tolerated and patient compliance was excellent. CONCLUSION: Glycolic acid chemical peels are an effective treatment for all types of acne, inducing rapid improvement and restoration to normal looking skin.
L Atzori; M A Brundu; A Orru; P Biggio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the European Academy of Dermatology and Venereology : JEADV     Volume:  12     ISSN:  0926-9959     ISO Abbreviation:  J Eur Acad Dermatol Venereol     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-07-01     Completed Date:  1999-07-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9216037     Medline TA:  J Eur Acad Dermatol Venereol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  119-22     Citation Subset:  IM    
Clinica Dermatologica Universita di Cagliari, Italy.
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MeSH Terms
Acne Vulgaris / classification,  drug therapy*
Cicatrix / prevention & control
Glycolates / administration & dosage,  therapeutic use*
Keratolytic Agents / administration & dosage,  therapeutic use*
Patient Compliance
Patient Satisfaction
Time Factors
Reg. No./Substance:
0/Glycolates; 0/Keratolytic Agents; 79-14-1/glycolic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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