| Glycolic acid peels versus amino fruit acid peels in the treatment of melasma. | |
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MedLine Citation:
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PMID: 20187899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Chemical peels are becoming more popular as a treatment modality for melasma. OBJECTIVE: To compare the therapeutic effects of glycolic acid (GA) peels and amino fruit acid (AFA) peels in patients with melasma. METHODS: In this single-blind, randomized right-left comparison study, patients received 12 serial peels on the two halves of the face at 2-week intervals for 6 months. Clinical evaluation based on the modified Melasma Area and Severity Index (MASI) scores was performed at baseline and at 3 and 6 months. RESULTS: The modified MASI scores at 3 and 6 months in both application areas decreased significantly from baseline (p<.05). When the two applications were compared with each other, there was no statistically significant difference between GA and AFA in terms of regression of melasma (p>.05). During the application, it was observed that AFA peels caused fewer problems than GA peels did. CONCLUSIONS: Based on the results of this study, GA and AFA peels for melasma therapy were efficacious, but the AFA peel was found to be less irritating and was better tolerated. |
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Authors:
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Turna Ilknur; Mehtap Unl? Bi?ak; Melda Demirta?o?lu; Sebnem Ozkan |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2010-02-19 |
Journal Detail:
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Title: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Volume: 36 ISSN: 1524-4725 ISO Abbreviation: Dermatol Surg Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-20 Completed Date: 2010-05-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9504371 Medline TA: Dermatol Surg Country: United States |
Other Details:
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Languages: eng Pagination: 490-5 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Faculty of Medicine, Dokuz Eyl?l University, Izmir, Turkey. turna.ilknur@deu.edu.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Cutaneous Adult Amino Acids / administration & dosage* Chemexfoliation / methods* Follow-Up Studies Fruit Glycolates / administration & dosage* Humans Keratolytic Agents / administration & dosage* Melanosis / therapy* Middle Aged Single-Blind Method Treatment Outcome Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Glycolates; 0/Keratolytic Agents; 79-14-1/glycolic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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