Document Detail

Glycogen storage in fetuses of trained pregnant rats.
MedLine Citation:
PMID:  9263621     Owner:  NLM     Status:  MEDLINE    
The purpose was to determine if running 30 m/min on a 10 degrees incline, 60 min/day for 5 days/ week altered fetal glycogen storage in prepregnancy trained rats. Animals that exercised for 3 weeks prior to pregnancy either continued the same exercise program until Day 19 of gestation (pregnant running group [PR]), or ceased exercising at conception (pregnant controls [PC]). A separate set of animals did not exercise either before or during pregnancy (pregnant nonrunning control group [PNRC]). On Day 20 of gestation, fetal organs and placenta were weighted and analyzed for glycogen concentration. Glycogen concentrations were not different in either fetal liver, heart, or placenta of PR rats compared to PNRC animals. However, fetal liver glycogen concentration was significantly lower in the fetal heart and liver of PC animals compared to glycogen measured in both PNRC and PR animals (p < .05). These results suggest that exercise of this intensity does not compromise fetal glycogen storage in trained pregnant rats. However, chronic prepregnancy exercise and then abrupt cessation of exercise at conception may compromise fetal growth and development.
P E Houghton; M F Mottola; J Mezzapelli; R Vandermolen; P D Christopher
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of applied physiology = Revue canadienne de physiologie appliquée     Volume:  22     ISSN:  1066-7814     ISO Abbreviation:  Can J Appl Physiol     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-10-06     Completed Date:  1997-10-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9306274     Medline TA:  Can J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  384-93     Citation Subset:  IM    
Department of Physical Therapy, Faculty of Applied Health Sciences, University of Western Ontario, London.
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MeSH Terms
Evaluation Studies as Topic
Fetus / metabolism*
Glycogen / metabolism*
Liver Glycogen / metabolism
Physical Conditioning, Animal / physiology*
Placenta / metabolism
Pregnancy, Animal / physiology*
Random Allocation
Rats, Sprague-Dawley
Reg. No./Substance:
0/Liver Glycogen; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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