Document Detail


Glycodelin serum levels in women with ectopic pregnancy.
MedLine Citation:
PMID:  12781411     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Aim of our study was to determine circulating levels of glycodelin for biochemical monitoring of women with vaginal bleeding and/or abdominal pain in early pregnancy. The objective was, using glycodelin as a biochemical parameter, to distinguish between incomplete abortion and ectopic pregnancy in early weeks of gestation. STUDY DESIGN: In 169 women with a first trimester pregnancy, a single serum measurement of maternal glycodelin was taken. Patients were divided into groups according to the clinical and/or ultrasonografic findings at the time of hospitalisation:ectopic pregnancy, incomplete abortion and control. RESULTS: Glycodelin serum levels were significantly lower in patients with ectopic pregnancy comparable with intact pregnancy and incomplete abortion. There was no difference in serum levels between intact pregnancy and incomplete abortion. CONCLUSION: Glycodelin might represent a biochemical parameter in the differential diagnosis between ectopic pregnancies and incomplete abortion. The number of patients was too small to give reference ranges for pregnancy weeks.
Authors:
Dolores Foth; Thomas Römer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  108     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-03     Completed Date:  2004-01-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  199-202     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, University of Cologne, Kerpener Strasse 34, 50931, Köln, Germany. dfoth@t-online.de
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MeSH Terms
Descriptor/Qualifier:
Abdominal Pain
Abortion, Incomplete / blood
Adult
Diagnosis, Differential
Female
Gestational Age
Glycoproteins / blood*
Humans
Pregnancy
Pregnancy Proteins / blood*
Pregnancy, Ectopic / blood*,  diagnosis*
Pregnancy, Tubal / blood
Uterine Hemorrhage
Chemical
Reg. No./Substance:
0/Glycoproteins; 0/PAEP protein, human; 0/Pregnancy Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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