Document Detail

Glycerol use in hyperhydration and rehydration: scientific update.
MedLine Citation:
PMID:  23075560     Owner:  NLM     Status:  In-Data-Review    
Glycerol ingestion creates an osmotic drive that enhances fluid retention. The major practical applications for athletes are to either (i) hyperhydrate before exercise so that they have more fluid to be lost as sweat during subsequent performance, thereby delaying the progression of dehydration from becoming physiologically significant, or (ii) improve both the rate of rehydration and total fluid retention following exercise. Recently we showed that rehydration may be improved further by combining glycerol with intravenous fluids. Improvements in endurance time, time trial performance and total power and work output have been seen during exercise following glycerol-induced hyperhydration or rehydration. Another recent trial showed that the increased body weight associated with the extra fluid does not inadvertently affect running economy. Concerns that the haemodilution associated with the fluid retention in the vascular space may be sufficient to mask illegal doping practices by athletes led the World Anti-Doping Agency (WADA) to add glycerol to its list of prohibited substances in 2010. Recent evidence suggests that doses of > 0.032 ± 0.010 g/kg lean body mass (much lower than those required for rehydration) will result in urinary excretion that may be detectable, so athletes under the WADA jurisdiction should be cautious to limit their inadvertent glycerol intake.
S P van Rosendal; J S Coombes
Publication Detail:
Type:  Journal Article     Date:  2012-10-15
Journal Detail:
Title:  Medicine and sport science     Volume:  59     ISSN:  1662-2812     ISO Abbreviation:  Med Sport Sci     Publication Date:  2013  
Date Detail:
Created Date:  2012-10-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402440     Medline TA:  Med Sport Sci     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  104-12     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Human Performance Laboratory, School of Human Movement Studies, The University of Queensland, Brisbane, Qld., Australia.
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