Document Detail


Glycemic responses to exercise in IDDM after simple and complex carbohydrate supplementation.
MedLine Citation:
PMID:  8725854     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Subjects with IDDM should take carbohydrate before exercise to avoid hypoglycemia. However, there is little information on the glycemic effect of recommended supplementation. This study is aimed to determine the glycemic effects of oral glucose or bread (30 g carbohydrate) before 45 min of moderate exercise. RESEARCH DESIGN AND METHODS: Nine subjects with uncomplicated IDDM did 45 min of bicycle ergometer exercise at 60% VO2max in the morning before insulin injection on three occasions: 1) with no carbohydrate supplement, 2) with 30 g glucose in water at -5 min, and 3) with 30 g carbohydrate as white bread with water at -20 min. The glycemic responses were determined. The glycemic responses to glucose and bread were also determined without exercise in six subjects. RESULTS: Without carbohydrate, exercise caused a small fall (-1.2 +/- 0.6 mmol/l, mean +/- SE) in plasma glucose (PG). With either glucose or bread, PG rose (the change in plasma glucose relative to basal [delta PG] = 5.1 +/- 0.8 and 2.6 +/- 0.8, respectively). The rise was greater (P < 0.01) without exercise (delta PG = 6.9 +/- 0.7 and 4.5 +/- 0.7, respectively). During exercise, glucose increased PG levels more than bread increased glucose levels P < 0.05). CONCLUSIONS: Before morning insulin injection, the fall in PG during moderate exercise in IDDM subjects is generally small or absent. The glycemic effects of complex carbohydrate are slightly less than glucose before exercise. Under these circumstances, the usually recommended amount of carbohydrate tends to cause an unwanted elevation of PG; thus, IDDM subjects should anticipate reducing or even omitting carbohydrate supplementation after monitoring their individual glycemic response.
Authors:
K Soo; S M Furler; K Samaras; A B Jenkins; L V Campbell; D J Chisholm
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diabetes care     Volume:  19     ISSN:  0149-5992     ISO Abbreviation:  Diabetes Care     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-11-05     Completed Date:  1996-11-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7805975     Medline TA:  Diabetes Care     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  575-9     Citation Subset:  IM    
Affiliation:
Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, Australia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Glucose / metabolism*
Bread*
Diabetes Mellitus, Type 1 / blood,  drug therapy,  physiopathology*
Dietary Carbohydrates*
Exercise Test*
Female
Glucose*
Heart Rate
Humans
Insulin / therapeutic use
Male
Oxygen Consumption
Physical Exertion*
Rest
Time Factors
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Dietary Carbohydrates; 11061-68-0/Insulin; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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