| The Glycemic Response Does Not Reflect the In Vivo Starch Digestibility of Fiber-Rich Wheat Products in Healthy Men. | |
| | |
MedLine Citation:
|
PMID: 22223569 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Starchy food products differ in the rate of starch digestion, which can affect their metabolic impact. In this study, we examined how the in vivo starch digestibility is reflected by the glycemic response, because this response is often used to predict starch digestibility. Ten healthy male volunteers [age 21 ± 0.5 y, BMI 23 ± 0.6 kg/m(2) (mean ± SEM)] participated in a cross-over study, receiving three different meals: pasta with normal wheat bran (PA) and bread with normal (CB) or purple wheat bran (PBB). Purple wheat bran was added in an attempt to decrease the rate of starch digestion. The meals were enriched in (13)C and the dual isotope technique was applied to calculate the rate of appearance of exogenous glucose (RaE). The (13)C-isotopic enrichment of glucose in plasma was measured with GC/combustion/isotope ratio MS (IRMS) and liquid chromatography/IRMS. Both IRMS techniques gave similar results. Plasma glucose concentrations [2-h incremental AUC (iAUC)] did not differ between the test meals. The RaE was similar after consumption of CB and PBB, showing that purple wheat bran in bread does not affect in vivo starch digestibility. However, the iAUC of RaE after men consumed PA was less than after they consumed CB (P < 0.0001) despite the similar glucose response. To conclude, the glycemic response does not always reflect the in vivo starch digestibility. This could have implications for intervention studies in which the glycemic response is used to characterize test products. |
| | |
Authors:
|
Coby Eelderink; Tanja C W Moerdijk-Poortvliet; Hongwei Wang; Marianne Schepers; Tom Preston; Theo Boer; Roel J Vonk; Henk Schierbeek; Marion G Priebe |
Related Documents
:
|
1547589 - Puberty and insulin-dependent diabetes mellitus. 2027939 - Eating disorders and intentional insulin undertreatment in adolescent females with diab... 22019949 - Diverging sex-specific long-term effects of cigarette smoking on fasting insulin and gl... 2667279 - Some salivary factors in insulin-dependent diabetics. 8857659 - Salivary factors in children and adolescents with insulin-dependent diabetes mellitus. 1885479 - Immunoclinical correlation in diabetes mellitus. a preliminary report on the lectin-agg... 8798359 - Localization of endocrine pancreatic islets. 19011009 - Baicalein reduces inflammatory process in a rodent model of diabetic retinopathy. 15356069 - Age-dependent regulation of lipogenesis in human and rat adipocytes. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-5 |
Journal Detail:
|
Title: The Journal of nutrition Volume: - ISSN: 1541-6100 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-6 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0404243 Medline TA: J Nutr Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Center for Medical Biomics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Factors Associated with Sugar-Sweetened Beverage Intake among United States High School Students.
Next Document: Lactobacillus rhamnosus GG and Bifidobacterium animalis MB5 Induce Intestinal but Not Systemic Antig...