| Glycated albumin may be a possible alternative to hemoglobin A(1c) in diabetic patients with anemia. | |
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MedLine Citation:
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PMID: 21679130 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Background: We assessed whether glycated albumin (GA) is a useful glycemic indicator in diabetic patients with anemia who did not undergo dialysis. Methods: Hemoglobin A(1c) (HbA(1c)) and GA were simultaneously measured in 370 diabetic subjects who had not undergone dialysis. The relationship between GA and HbA(1c) was evaluated in patients with and without anemia. Results: GA-to-HbA(1c) ratio was significantly higher (3.3±0.7 vs. 2.8±0.5, p<0.001) and the regression slope between GA and HbA(1c) was steeper in diabetic patients with than in those without anemia (6.2 vs. 4.2, p<0.001). Conclusions: HbA(1c) was underestimated in diabetic patients with anemia than in those without anemia, with the degree of underestimation increasing as glycemic control became poorer. GA may more accurately assess glycemic control in diabetic patients with anemia than HbA(1c). |
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Authors:
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Sollip Kim; Won-Ki Min; Sail Chun; Woochang Lee; Hae-Il Park |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-17 |
Journal Detail:
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Title: Clinical chemistry and laboratory medicine : CCLM / FESCC Volume: - ISSN: 1434-6621 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9806306 Medline TA: Clin Chem Lab Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Laboratory Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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