| Glycan-Specific Metabolic Oligosaccharide Engineering of C7-Substituted Sialic Acids. | |
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MedLine Citation:
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PMID: 22644729 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A biosynthetic method using a synthetic C4-modified mannosamine derivative provides the previously inaccessible C7 modifications of sialic acids in living cells. S. Hinderlich, C. P. R. Hackenberger, and co-workers also show in their Communication (10.1002/anie.201108809) that their synthetic mannosamine derivative could label the membrane-associated glycoproteins of live animals. The picture shows the "machinery" which converts the new mannosamine compound into sialic acid and transports it to glycoproteins on the cell surface. (© O'Reilly Science Art). |
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Authors:
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Heinz Möller; Verena Böhrsch; Joachim Bentrop; Judith Bender; Stephan Hinderlich; Christian P R Hackenberger |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-29 |
Journal Detail:
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Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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