Document Detail

Glutathione in Tetrahymena thermophila.
MedLine Citation:
PMID:  2709339     Owner:  NLM     Status:  MEDLINE    
In Tetrahymena, glutathione is synthesized from the same precursors as it is in higher animals and is present in similar intracellular concentrations. The intracellular thiol-disulfide ratio is also identical to that of mammalian tissues, due to the activity of glutathione reductase. The intracellular GSH-level was found to be dependent on the sulfur-containing amino acids in the chemically defined medium.
B Wagner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of protozoology     Volume:  36     ISSN:  0022-3921     ISO Abbreviation:  J. Protozool.     Publication Date:    1989 Jan-Feb
Date Detail:
Created Date:  1989-06-06     Completed Date:  1989-06-06     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  2985197R     Medline TA:  J Protozool     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  92-5     Citation Subset:  IM    
Institute of Biochemistry, University of Heidelberg, Federal Republic of Germany.
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MeSH Terms
Cystine / pharmacology
Cytoplasm / analysis
Glutathione / analysis*,  metabolism
Glutathione Reductase / metabolism
Methionine / pharmacology
Tetrahymena / analysis*,  drug effects,  enzymology
Reg. No./Substance:
56-89-3/Cystine; 63-68-3/Methionine; 70-18-8/Glutathione; EC Reductase

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