Document Detail


Glutathione, L-glutamic acid and gamma-glutamyl transpeptidase in the bull reproductive tissues.
MedLine Citation:
PMID:  2897339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The distribution of glutathione (GSH), L-glutamic acid (Glu) and gamma-glutamyl transpeptidase (gamma-GT) was studied in bull reproductive organs and fluids. Glutathione, the physiological substrate of gamma-GT, was localized specifically by a fluorescence method in the testis, epididymis and spermatozoa. Of the reproductive tissues, the testis, caput epididymis and ampulla had the highest levels of GSH, but it was also present in seminal fluid. Washed caput epididymal sperm had three times the GSH content of cauda epididymal or ejaculated sperm. In spermatozoa, GSH displayed maximal staining in the midpiece and tail regions. The highest levels of gamma-GT were encountered in the epididymis. The concentration of Glu was also high in the epididymis. Its formation may be due to the hydrolytic activity of gamma-GT, which, in addition, may have an important role in the transfer of Glu residues to reactive groups on the sperm surface.
Authors:
Y P Agrawal; T Vanha-Perttula
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of andrology     Volume:  11     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-06-29     Completed Date:  1988-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  123-31     Citation Subset:  IM    
Affiliation:
Department of Anatomy, University of Kuopio, Finland.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cattle
Chromatography, High Pressure Liquid
Genitalia, Male / analysis*
Glutamates / analysis*
Glutamic Acid
Glutathione / analysis*
Histocytochemistry
Male
Spectrometry, Fluorescence
Spermatozoa / analysis*
Testis / analysis
gamma-Glutamyltransferase / analysis*
Chemical
Reg. No./Substance:
0/Glutamates; 56-86-0/Glutamic Acid; 70-18-8/Glutathione; EC 2.3.2.2/gamma-Glutamyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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