Document Detail


Glucose therapy of recurrent lactic acidosis.
MedLine Citation:
PMID:  742638     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lactic acidosis not associated with hypoxic states has a high morbidity and mortality. Treatment of this condition has been supportive and the etiology poorly understood. We report a case of recurrent lactic acidosis in a patient with renal and hepatic insufficiency with hypoglycemia which was repeatedly reversed by restoring the glucose concentration to normal. This case and several others in the literature suggest a mechanism for the development of type II B hyperlactatemia and new approaches for therapy.
Authors:
L C Maguire; B M Sherman; J E Whalen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  276     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:    1978 Nov-Dec
Date Detail:
Created Date:  1979-04-28     Completed Date:  1979-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  305-17     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Acidosis / drug therapy*,  etiology,  metabolism
Adult
Glucose / therapeutic use*
Humans
Hypoglycemia / complications,  drug therapy,  metabolism
Kidney Diseases / metabolism
Lactates / metabolism*
Liver Diseases / metabolism
Male
Oxygen Consumption
Pyruvates / metabolism
Recurrence
Chemical
Reg. No./Substance:
0/Lactates; 0/Pyruvates; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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