Document Detail


Glucose and maltodextrin in enteral diets have different effects on jejunal absorption of nutrients, sodium and water and on flow rate in mini pigs.
MedLine Citation:
PMID:  9932013     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In four mini pigs a segment of the proximal jejunum was temporarily isolated and perfused with two enteral diets containing isocaloric amounts either of glucose or maltodextrin. With regard to total energy, the diets were composed of 60% carbohydrate, 20% protein and 20% fat. The perfusion rates were 1, 2, 4, 6, and 8 kcal/min. Absorption of glucose and fat from the maltodextrin diet was significantly greater than from the glucose diet, whereas absorption of protein was only slightly enhanced. A net water absorption occurred at perfusion of the isotonic solution with maltodextrin. Perfusing the hypertonic glucose diet, water was secreted. Therefore the flow rate increased from oligomer to monomer glucose source. With enhanced flow rate sodium secretion increased. However, the sodium concentration of the effluent was determined more by the transepithelial water movement than by the sodium secretion. The present results indicate that in enteral diets with interactions among different nutrients there is a 'kinetic advantage' in glucose absorption from maltodextrin compared to glucose. However, the reduced flow rate of the maltodextrin diet due to the lower osmolality contributed to the enhanced absorption.
Authors:
E Weber; H J Ehrlein
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  DTW. Deutsche tierärztliche Wochenschrift     Volume:  105     ISSN:  0341-6593     ISO Abbreviation:  DTW. Dtsch. Tierarztl. Wochenschr.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-03-15     Completed Date:  1999-03-15     Revised Date:  2007-07-24    
Medline Journal Info:
Nlm Unique ID:  7706565     Medline TA:  Dtsch Tierarztl Wochenschr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  446-9     Citation Subset:  IM    
Affiliation:
Institute of Physiology, University of Hohenheim, Stuttgart, Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Enteral Nutrition
Female
Glucose / metabolism*,  pharmacology*
Intestinal Absorption / drug effects,  physiology*
Jejunum / physiology*
Polysaccharides / metabolism*,  pharmacology*
Sodium / metabolism
Swine
Swine, Miniature
Water / metabolism
Chemical
Reg. No./Substance:
0/Polysaccharides; 50-99-7/Glucose; 7440-23-5/Sodium; 7732-18-5/Water; 9050-36-6/maltodextrin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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