| Glucose infusions into peripheral veins in the management of neonatal hypoglycemia--20% instead of 15%? | |
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MedLine Citation:
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PMID: 19397539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To establish whether peripheral intravenous 20% glucose solutions would cause less local irritation, fewer cannulation changes and less weight gain than 15% glucose in newborn infants. METHODS: A total of 121 newborn infants with hypoglycemia were randomized to receive either 20% (group 20%, 60 infants) or 15% (group 15%, 61 infants) glucose infusions, which were initiated at 8 mg/kg/min rates and tapered according to the blood glucose levels. When the cannulation site had to be changed, signs of phlebitis at the previous cannulation site were scored (0-3). Number of cannulation site changes, durations of infusions and the infants' daily weights were recorded. RESULTS: The median durations of infusions in groups 20 and 15% were 4 (range 2-7) days versus 4 (range 2-8) days and the median number of cannulation site changes were 1 (range 0-6) versus 1 (range 0-5), respectively. Thirty-six infants in group 20% and 37 in group 15% developed some phlebitis, median severity scores being 1 (range 0-7) versus 15% 1 (range 0-8). The weights during the treatment were also similar. CONCLUSION: 20% and 15% glucose solutions can be infused equally safely into peripheral veins in neonates. |
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Authors:
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T Vanhatalo; O Tammela |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2009-04-14 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 99 ISSN: 1651-2227 ISO Abbreviation: Acta Paediatr. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-31 Completed Date: 2010-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: Norway |
Other Details:
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Languages: eng Pagination: 350-3 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Pediatric Research Centre, Tampere University Hospital, Tampere, Finland. outi.tammela@uta.fi |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Catheterization, Peripheral Female Glucose / administration & dosage*, adverse effects Humans Hypoglycemia / drug therapy* Infant, Newborn Infusions, Intravenous Male Phlebitis / chemically induced Severity of Illness Index Treatment Outcome Weight Gain |
| Chemical | |
Reg. No./Substance:
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50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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