Document Detail

Glucometabolic state in Chinese patients undergoing elective coronary angiography.
MedLine Citation:
PMID:  21185615     Owner:  NLM     Status:  MEDLINE    
AIM: The aim of this study is to characterize the glucometabolic state of patients undergoing elective coronary angiography (CA) in a subpopulation in China.
METHODS AND RESULTS: This study recruited 896 patients undergoing elective CA for the evaluation of suspected coronary artery disease (CAD). Oral glucose tolerance tests (OGTTs) performed in patients without previously known diabetes revealed that 173 (19.2%) had newly diagnosed diabetes and 281 (31.5%) had impaired glucose regulation. The prevalence of abnormal glucose metabolism (AGM) was significant difference among three groups of CA diagnosis, including normal coronary, nonsignificant stenosis and CAD. Overall, the proportion of patients with type 2 diabetes increased from 22.0% at baseline to 41.2% post-OGTT analysis. In total, 270 (59.5%) patients with AGM would have remained undetected if OGTTs had not been performed. Patients with CAD, hypertension, dyslipidemia, obesity and high C-reactive protein levels were at high risk of AGM.
CONCLUSIONS: AGM is common and underestimated by FPG testing alone in patients undergoing elective CA. OGTTs should be routinely performed to assess the glucometabolic state of patients undergoing elective CA, especially in patients with high risks of AGM. Detecting the state of AGM in CA individuals may provide strategies to reduce the progression of AGM and associated complications.
Zhu-Zhi Wen; Dong-mei Jin; Ya-mei Zhang; Jing-Feng Wang; Deng-Feng Geng
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Publication Detail:
Type:  Journal Article     Date:  2011-01-06
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  91     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-11     Completed Date:  2011-08-08     Revised Date:  2011-09-09    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  300-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Department of Cardiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
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MeSH Terms
Asian Continental Ancestry Group
Coronary Angiography*
Coronary Artery Disease / diagnosis*,  epidemiology,  metabolism
Diabetes Mellitus, Type 2 / diagnosis*,  epidemiology
Glucose / metabolism*
Glucose Tolerance Test
Middle Aged
Risk Factors
Reg. No./Substance:
Erratum In:
Diabetes Res Clin Pract. 2011 Jul;93(1):132

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