Document Detail

Glucocorticoids for acute viral bronchiolitis in infants and young children.
MedLine Citation:
PMID:  24381968     Owner:  NLM     Status:  MEDLINE    
CLINICAL QUESTION: Are glucocorticoids, alone or combined with bronchodilators, associated with reduced admission rates, length of stay, or improvements in clinical severity scores without increased adverse effects in infants and young children with acute viral bronchiolitis?
BOTTOM LINE: There is no consistent clinically relevant association of single therapy with systemic or inhaled glucocorticoids and improved outcomes in either outpatient or inpatient settings. Exploratory evidence suggests that combined glucocorticoids and nebulized epinephrine may be associated with lower hospitalization rates in outpatients, but these findings must be interpreted cautiously.
Ricardo M Fernandes; Lisa Hartling
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  JAMA     Volume:  311     ISSN:  1538-3598     ISO Abbreviation:  JAMA     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-01-01     Completed Date:  2014-01-13     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  United States    
Other Details:
Languages:  eng     Pagination:  87-8     Citation Subset:  AIM; IM    
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MeSH Terms
Bronchiolitis, Viral / drug therapy*
Glucocorticoids / therapeutic use*
Reg. No./Substance:
Comment On:
Cochrane Database Syst Rev. 2013;6:CD004878   [PMID:  23733383 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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