Document Detail

Glucocorticoid use represents a risk factor for central serous chorioretinopathy: a prospective, case-control study.
MedLine Citation:
PMID:  14986014     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate whether exposure to glucocorticoids represents a risk factor for the development of central serous chorioretinopathy (CSCR). METHODS: Prospective, case-control study. Thirty-eight consecutive patients with acute CSCR were asked to answer a specific questionnaire regarding the use of glucocorticoids, in any form, during the last month before the onset of the symptoms. An age- and sex-matched control group was also recruited. It consisted of patients attending the outpatient department for a condition other than CSCR, who were asked to answer the same questionnaire. RESULTS: Use of glucocorticoids was recorded in 11 of 38 patients (28.9%) with CSCR; 8 of them were men and 3 women. In the control group, use of glucocorticoids was recorded in 2 of 38 patients (5.2%), 1 man and 1 woman. The difference between the two groups is statistically significant (odds ratio=7.33, 95% CI=1.49-35.85, P=0.006). CONCLUSION: In this prospective, case-control study, we found that glucocorticoid use represents a risk factor for the development of CSCR.
Panagiotis Karadimas; Evrydiki A Bouzas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie     Volume:  242     ISSN:  0721-832X     ISO Abbreviation:  Graefes Arch. Clin. Exp. Ophthalmol.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2005-01-27     Completed Date:  2005-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8205248     Medline TA:  Graefes Arch Clin Exp Ophthalmol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  800-2     Citation Subset:  IM    
Medical Retina Unit, 1st Department of Ophthalmology, Henry Dunant Hospital, 107 Mesogion Avenue, 11526 Athens, Greece.
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MeSH Terms
Case-Control Studies
Choroid Diseases / chemically induced*
Exudates and Transudates
Glucocorticoids / adverse effects*
Middle Aged
Prospective Studies
Retinal Diseases / chemically induced*
Risk Factors
Reg. No./Substance:

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