| Glucagon stimulation test for estimating endogenous insulin secretion in dogs. | |
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MedLine Citation:
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PMID: 18757903 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fifty-one dogs (27 diabetic dogs, four that had recovered from diabetes and 20 healthy control dogs) were given 0.5 or 1.0 mg glucagon intravenously. Blood samples were taken before the injection and 10 and 20 minutes after it. Samples were analysed to determine C-peptide, insulin and glucose concentrations, and one sample from each dog was analysed for fructosamine. The median (interquartile range) concentrations of C-peptide in the samples taken at 10 minutes were 0.5 (0.3 to 0.8) nmol/l in the control dogs, 0.1 (0 to 0.2) nmol/l in the diabetic dogs, and 0.3 (0.2 to 0.4) nmol/l in the dogs that had recovered from diabetes. Seven of the 51 dogs showed mild adverse reactions after the injection of glucagon. |
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Authors:
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T Fall; B Holm; A Karlsson; K M Ahlgren; O Kämpe; H von Euler |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Veterinary record Volume: 163 ISSN: 0042-4900 ISO Abbreviation: Vet. Rec. Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-09-01 Completed Date: 2009-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0031164 Medline TA: Vet Rec Country: England |
Other Details:
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Languages: eng Pagination: 266-70 Citation Subset: IM |
Affiliation:
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Department of Clinical Sciences, Swedish University of Agricultural Sciences (SLU), SE-750 07 Uppsala, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Glucose / analysis C-Peptide / blood Diabetes Mellitus / blood, diagnosis, drug therapy, veterinary* Dog Diseases / blood, diagnosis*, drug therapy Dogs Female Fructosamine / blood Glucagon / administration & dosage, adverse effects, diagnostic use* Glucose Tolerance Test Hypoglycemic Agents / therapeutic use Insulin / blood, secretion*, therapeutic use Male Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/C-Peptide; 0/Hypoglycemic Agents; 11061-68-0/Insulin; 4429-04-3/Fructosamine; 9007-92-5/Glucagon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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