Document Detail


Glomerulonephritis in ankylosing spondylitis.
MedLine Citation:
PMID:  3516479     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There have been a few reports suggesting the association between glomerulonephritis (GN) and ankylosing spondylitis (AS). The reported glomerulonephritides include IgA nephropathy, mesangial proliferative GN and membranous nephropathy. From January 1983, through December 1984, we observed 5 cases of GN among 116 cases of definite AS. Three of them were IgA nephropathy. The other two were mesangial proliferative GN, with IgM deposit in one case and isolated C3 deposit in another. Microscopic hematuria was observed in all of them. The renal function and 24-hour urine protein excretion were all within normal limits. Serum IgA level increased in all but the case of mesangial proliferative GN with IgM deposit. All except one had the antigen of HLA-B27. Serum IgA level was determined in 78 cases (86 estimations) of AS. The mean value was 399.6 +/- 15.0 mg/dl (mean +/- SE) (normal range: 100-350 mg/dl). Fifty-four of them (63%) had a value higher than 350 mg/dl. The interrelationship of AS and IgA nephropathy was discussed.
Authors:
K H Shu; J D Lian; Y F Yang; Y S Lu; J Y Wang; J L Lan; G Chou
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  25     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1986 Apr 
Date Detail:
Created Date:  1986-06-03     Completed Date:  1986-06-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  169-74     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Complement C3 / immunology
Fluorescent Antibody Technique
Glomerulonephritis / complications*,  immunology
Glomerulonephritis, IGA / complications*,  immunology
HLA Antigens / immunology
HLA-B27 Antigen
Humans
Immunoglobulin A / immunology
Immunoglobulin M / immunology
Male
Spondylitis, Ankylosing / complications*,  immunology
Chemical
Reg. No./Substance:
0/Complement C3; 0/HLA Antigens; 0/HLA-B27 Antigen; 0/Immunoglobulin A; 0/Immunoglobulin M

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