Document Detail

Glomerulonephritis associated with tuberculosis: A case report and literature review.
MedLine Citation:
PMID:  23684140     Owner:  NLM     Status:  In-Data-Review    
Rapidly progressive glomerulonephritis caused mycobacterium tuberculosis is rare; however, three case have been reported to date. Crescentic glomerulonephritis is a life-threatening disease and together with the presence of tuberculous infection is associated with a poor outcome if treatment is inadequate and delayed. We describe the case of a 31-year-old female patient with nephrotic syndrome and progressive renal failure secondary to pulmonary tuberculosis. Renal biopsy showed crescent formation in 14 out of 27 glomeruli, and there was diffuse linear staining of immunoglobulin G deposits. Treatment included corticosteroids in combination with antituberculosis drugs for 2 months, and resulted in a significant improvement in renal function, the disappearance of proteinuria and pulmonary symptoms. We also present a review of the pertinent literature and discuss the pathophysiology of tuberculosis-related acute postinfectious glomerulonephritis.
Yalcin Solak; Abduzhappar Gaipov; Melih Anil; Huseyin Atalay; Orhan Ozbek; Kultigin Turkmen; Ilker Polat; Suleyman Turk
Publication Detail:
Type:  Journal Article     Date:  2013-01-16
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  29     ISSN:  1607-551X     ISO Abbreviation:  Kaohsiung J. Med. Sci.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  337-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2012. Published by Elsevier B.V.
Division of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, Turkey. Electronic address:
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