| Glomeruloid hemangioma. A cutaneous marker of POEMS syndrome. | |
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MedLine Citation:
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PMID: 8030771 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glomeruloid hemangioma is a histologically distinctive cutaneous hemangioma that recently has been associated with POEMS syndrome. We report a further case in which POEMS syndrome was signaled by multiple eruptive angiomas of the glomeruloid type. Histopathology showed multiple dilated vascular spaces containing a conglomerate of capillaries resulting in a structure resembling renal glomeruli. Eosinophilic globules, probably representing immunoglobulins, were found within the cytoplasm of some endothelial and stromal cells. The finding of focal histologic features of tufted angioma (angioblastoma) in the same lesion suggests that a spectrum of hemangiomatous lesions may be seen in POEMS syndrome. Alternatively, glomeruloid hemangioma may represent a reactive endothelial proliferation rather than a neoplastic lesion. |
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Authors:
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F Rongioletti; C Gambini; R Lerza |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The American Journal of dermatopathology Volume: 16 ISSN: 0193-1091 ISO Abbreviation: Am J Dermatopathol Publication Date: 1994 Apr |
Date Detail:
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Created Date: 1994-08-11 Completed Date: 1994-08-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7911005 Medline TA: Am J Dermatopathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 175-8 Citation Subset: IM |
Affiliation:
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University of Genoa, Department of Dermatology, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Hemangioma
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pathology* Humans Male Middle Aged POEMS Syndrome / pathology* Skin / pathology Skin Neoplasms / pathology* |
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