| Glomerular filtration changes during vasotocin-induced antidiuresis in kelp gulls. | |
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MedLine Citation:
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PMID: 3202226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In conscious kelp gulls, intravenous infusion of arginine vasotocin (AVT) at rates of 0.03, 0.1, 0.3, and 1.0 ng.kg-1.min-1 resulted in a linear relationship between the log values of the AVT plasma concentrations (measured by radioimmunoassay) and the infusion rates, which indicated a plasma clearance rate for AVT of 15.4 ml.min-1.kg-1 when endogenous AVT formation is considered. Evaluation of the renal actions of AVT at each dose level showed that antidiuresis was consistently associated with reductions in glomerular filtration rate as well as changes in tubule water permeability. Thus the water-conserving action of plasma AVT on the kelp gull kidney involves contributions from both glomerular and tubular mechanisms over the entire physiological range found in these birds. |
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Authors:
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D A Gray; T Erasmus |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of physiology Volume: 255 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1988 Dec |
Date Detail:
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Created Date: 1989-01-26 Completed Date: 1989-01-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R936-9 Citation Subset: IM |
Affiliation:
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Department of Zoology, University of Port Elizabeth, South Africa. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Birds / physiology* Diuresis / drug effects Dose-Response Relationship, Drug Glomerular Filtration Rate / drug effects Kidney / drug effects, physiology* Male Reference Values Vasotocin / blood, pharmacology* |
| Chemical | |
Reg. No./Substance:
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9034-50-8/Vasotocin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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