Document Detail


Globus pallidus calcification in Down syndrome with progressive neurologic deficits.
MedLine Citation:
PMID:  1532715     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 10-year-old Down syndrome patient who developed dystonia, choreoathetosis, dysarthria, and dysphagia beginning with hemiparesis. Cranial computed tomography disclosed bilateral calcification in the globus pallidus which resembled a sign of premature aging. Conversely, the clinical course and magnetic resonance imaging findings resembled those of Hallervorden-Spatz syndrome.
Authors:
S Okano; Y Takeuchi; E Kohmura; H Yoshioka; T Sawada
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  8     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:    1992 Jan-Feb
Date Detail:
Created Date:  1992-05-11     Completed Date:  1992-05-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  72-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Bone Marrow / pathology
Calcinosis / diagnosis*,  pathology
Child
Diagnosis, Differential
Down Syndrome / diagnosis*,  pathology
Globus Pallidus / pathology*
Hemiplegia / diagnosis,  pathology
Humans
Magnetic Resonance Imaging
Male
Neurologic Examination
Neuromuscular Diseases / diagnosis*,  pathology
Pantothenate Kinase-Associated Neurodegeneration / diagnosis*,  pathology
Sea-Blue Histiocyte Syndrome / diagnosis,  pathology
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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