Document Detail

Globus pallidus alterations and brain atrophy in liver cirrhosis patients with encephalopathy: an MR imaging study.
MedLine Citation:
PMID:  1881246     Owner:  NLM     Status:  MEDLINE    
Brain magnetic resonance (MR) was performed in 29 liver cirrhosis patients without (N = 10) and with hepatic encephalopathy (HE) of chronic recurrent (N = 10) and of chronic persistent (N = 9) type. Sixty percent of the patients with chronic recurrent HE and 100% of the patients with chronic persistent HE showed a bilateral and symmetrical hyperintensity of the globus pallidus in the T1-weighted images while the T2-weighted images were normal, suggesting the possibility of the accumulation of a paramagnetic compound in this brain area during HE. Other findings of the study were evidence of brain atrophy of mild or moderate degree in 70% of patients with chronic recurrent HE and in 77% with chronic persistent HE and patients with liver cirrhosis without HE appeared normal on MR examination.
M L Zeneroli; G Cioni; G Crisi; C Vezzelli; E Ventura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Magnetic resonance imaging     Volume:  9     ISSN:  0730-725X     ISO Abbreviation:  Magn Reson Imaging     Publication Date:  1991  
Date Detail:
Created Date:  1991-10-03     Completed Date:  1991-10-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8214883     Medline TA:  Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  295-302     Citation Subset:  IM    
Clinica Medica III dell'Universitá di Modena, Italy.
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MeSH Terms
Brain / pathology*
Chronic Disease
Globus Pallidus / pathology
Hepatic Encephalopathy / etiology,  pathology*
Liver Cirrhosis / complications*,  pathology
Liver Cirrhosis, Alcoholic / complications,  pathology
Magnetic Resonance Imaging*
Middle Aged

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