Document Detail


Gliosis in Neonatal SUDI cases.
MedLine Citation:
PMID:  21767309     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aim:  To review sudden unexpected infants deaths (SUDI) in the first 28 days of life referred to a Coronial Perinatal Forensic Pathology Service over a 10-year period from 2000 to 2009. Methods:  Cases were collected from mortuary records and a retrospective review of autopsy reports, and other available infant records was undertaken. Results:  Twenty-four neonatal SUDI deaths were reviewed. For eight infants a diagnosis was found at autopsy. For the remaining 16 infants, 14 (87.5%) were bedsharing at the time of death. Maori infants and those living in deprived neighbourhoods were over-represented. Only two infants were preterm and four were growth restricted. At postmortem white matter gliosis was found in 10 of the 16 (62.5%) unexplained SUDI cases. Conclusion:  SUDI deaths occur in the first month of life in association with bedsharing. Gliosis may be an important associated risk factor and its presence indicates a previous insult of prenatal onset.
Authors:
May Chiu; Dawn Elder; Jane Zuccollo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-18
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Affiliation:
Medical Student Dept of Paediatrics & Child Health Dept Obstetrics & Gynaecology University of Otago Wellington PO Box 7343, Wellington South, New Zealand.
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