| Gliosis in the amygdala following myocardial infarction in the rat. | |
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MedLine Citation:
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PMID: 20379081 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We observed gliosis with cell death in the rat amygdala 3 and 14 days after myocardial infarction (MI). Cresyl violet-positive neurons had condensed cytoplasm, and Fluoro-Jade B-positive cells were detected in the amygdala 14 days, not 3 days, after MI. Only a few glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes and ionized calcium-binding adapter molecule 1 (Iba-1)-immunoreactive microglia showed activated form; hypertrophied cytoplasm, and highly ramified and retracted processes of astrocytes and microglia in the amygdala at 3 days after MI, respectively. At 14 days after MI, many astrocytes and most of microglia showed activated forms. These results suggest that MI may induce neuronal death and reactive gliosis in the amygdala. |
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Authors:
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Eunjoo Bae; In Koo Hwang; Ki-Yeon Yoo; Tae Hee Han; Choong Hyun Lee; Jung Hoon Choi; Sun Shin Yi; So Yeong Lee; Pan Dong Ryu; Yeo Sung Yoon; Moo-Ho Won |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-04-06 |
Journal Detail:
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Title: The Journal of veterinary medical science / the Japanese Society of Veterinary Science Volume: 72 ISSN: 0916-7250 ISO Abbreviation: J. Vet. Med. Sci. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-09-08 Completed Date: 2010-11-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105360 Medline TA: J Vet Med Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 1041-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon, South Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amygdala
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immunology,
pathology* Animals Astrocytes / pathology B-Lymphocytes / pathology Calcium-Binding Proteins / analysis Cell Death Cytoplasm / pathology Glial Fibrillary Acidic Protein / analysis Gliosis / etiology, immunology, veterinary* Major Histocompatibility Complex Myocardial Infarction / complications, immunology, pathology, veterinary* Myocardium / pathology Neurons / immunology, pathology Rats Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Aif1 protein, rat; 0/Calcium-Binding Proteins; 0/Glial Fibrillary Acidic Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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