Document Detail


Gliosis in the amygdala following myocardial infarction in the rat.
MedLine Citation:
PMID:  20379081     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We observed gliosis with cell death in the rat amygdala 3 and 14 days after myocardial infarction (MI). Cresyl violet-positive neurons had condensed cytoplasm, and Fluoro-Jade B-positive cells were detected in the amygdala 14 days, not 3 days, after MI. Only a few glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes and ionized calcium-binding adapter molecule 1 (Iba-1)-immunoreactive microglia showed activated form; hypertrophied cytoplasm, and highly ramified and retracted processes of astrocytes and microglia in the amygdala at 3 days after MI, respectively. At 14 days after MI, many astrocytes and most of microglia showed activated forms. These results suggest that MI may induce neuronal death and reactive gliosis in the amygdala.
Authors:
Eunjoo Bae; In Koo Hwang; Ki-Yeon Yoo; Tae Hee Han; Choong Hyun Lee; Jung Hoon Choi; Sun Shin Yi; So Yeong Lee; Pan Dong Ryu; Yeo Sung Yoon; Moo-Ho Won
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-06
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  72     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-08     Completed Date:  2010-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1041-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Amygdala / immunology,  pathology*
Animals
Astrocytes / pathology
B-Lymphocytes / pathology
Calcium-Binding Proteins / analysis
Cell Death
Cytoplasm / pathology
Glial Fibrillary Acidic Protein / analysis
Gliosis / etiology,  immunology,  veterinary*
Major Histocompatibility Complex
Myocardial Infarction / complications,  immunology,  pathology,  veterinary*
Myocardium / pathology
Neurons / immunology,  pathology
Rats
Time Factors
Chemical
Reg. No./Substance:
0/Aif1 protein, rat; 0/Calcium-Binding Proteins; 0/Glial Fibrillary Acidic Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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