Document Detail

Gliomatosis cerebri: bioptical approach and neuropathological verification.
MedLine Citation:
PMID:  1799156     Owner:  NLM     Status:  MEDLINE    
Gliomatosis cerebri is rarely encountered and its intra vitam diagnosis has remained difficult. We present biopsy and autopsy findings in three cases that are representative of diffuse glioma, gliomatosis cerebri and diffuse glioblastosis, a modification of the subclassification proposed by Zülch31. Stereotactic biopsy in conjunction with nuclear magnetic resonance tomography (MRT) is recommended as the diagnostic procedure in suspected cases. Immunohistochemical examination with a panel of neuroectodermal markers is helpful in the differential diagnosis but has to take into account that reactive astrocytes may be closely intermingled with the neoplastic glial cells.
R Schober; J K Mai; B Volk; W Wechsler
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neurochirurgica     Volume:  113     ISSN:  0001-6268     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  1991  
Date Detail:
Created Date:  1992-04-16     Completed Date:  1992-04-16     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  AUSTRIA    
Other Details:
Languages:  eng     Pagination:  131-7     Citation Subset:  IM    
Department of Neuropathology, Heinrich-Heine-University, Düsseldorf, Federal Republic of Germany.
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MeSH Terms
Astrocytes / pathology
Brain / pathology
Brain Neoplasms / pathology*,  therapy
Combined Modality Therapy
Glial Fibrillary Acidic Protein / analysis*
Glioma / pathology*,  therapy
Immunoenzyme Techniques
Middle Aged
Stereotaxic Techniques
Tumor Markers, Biological / analysis*
Reg. No./Substance:
0/Glial Fibrillary Acidic Protein; 0/Tumor Markers, Biological

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